The most researched SARM – Ostarine
Ostarine, also known as MK-2866 is Selective Androgen Receptor Modulator. (Read our article about Sarms and pro hormones if you do not know what they are). This Sarm is used to treat and prevent muscle wasting and weak bone health. It can also be used to cure and avoid Sarcopenia, Cachexia and Atrophy.
Ostarine has gained popularity, mainly, among people looking to reduce body fat while building muscle and increase strength. It is very hard without using supplements. Ostarine is the best Sarm when it comes to making this happen an easier way. According to research, there have not been found any side effects compare to steroids. That is the reason for the high approval and popularity.
Ostarine is basically the perfect Selective Androgen Receptor Modulator that could prevent muscle wasting and reduce the risk of benign prostatic hyperplasia.
Phase-I Human clinical trials happened. The results were said to be extremely positive. This is a huge step forward compare to other Sarms that only have been tested on the animals. Bodybuilders use to call Ostarine as the perfect SARM, it is mainly due to the many tests that have been done. In fact, many of them compare Ostarine to the Anavar which is “weaker” anabolic steroid that has not got many side effects, if taken in correct dosages.
To sum up, Ostarine is probably the most researched SARM out there, tested on humans and gaining popularity among bodybuilders that are switching to Ostarine from Anavar. But what does it bring to the table for an athlete, a bodybuilder or an amateur trying to break their threshold?
Let’s find out.
What is Ostarine?
Ostarine, MK-2866, GTx-024 or Enobosarm is a SARM that is developed and researched by GTx laboratories as a potential therapeutic aid to prevent muscle wasting caused due to cancer. As we briefly mentioned, it has been extensively studied. In fact, GTx still has studies underway on Ostarine after more than a decade and a half.
GTx-024 treatment resulted in dose-dependent increases in total lean body mass that were statistically significant (P < 0.001, 3 mg vs. placebo) and clinically meaningful. There were also significant improvements in physical function (P = 0.013, 3 mg vs. placebo) and insulin resistance (P = 0.013, 3 mg vs. placebo). The incidence of adverse events was similar between treatment groups.
That in itself speaks volumes about its perceived potential therapeutic uses. One day, it might replace a lot of side-effect inducing medicines that we use.
But if not for the bodybuilding community, Ostarine would be an unknown research chemical at best. Bodybuilders started to tap into it way back in the early 2000s once the research data became public and since then, it has remained one of the most popular SARMS in the world. Professional sporting organizations along with WADA have banned Ostarine way back in 2008 labelling it an ‘S1 Anabolic Agent’.
How Does Ostarine Works?
The given product tries to work by combining the protein in your body in a synergic way. This working mechanism could be very easily compared to that of anabolism wherein small molecules may combine to form a larger more complex form.
This process could require energy from an external source, which in this case, might come from this supplement- Ostarine. This product may as well make the protein in your body work harder and your muscles could grow bigger as you work out.
Ostarine could also help in increasing endurance levels for longer workout sessions. This might help you build your form even when you are feeling very tired due to the weight shredding diet.
It may as well ensure that the muscle lost during the workout hours could be recovered as soon as possible and adds increased muscle mass activity. Overall, it could make your body appear leaner and clean-cut.
According to the some of resources, It could also contain a number of different amino acids, including Leucine which is commonly used as a meal replacement supplement by bodybuilders.
Leucine may as well help to speed up muscle recovery time and could also help to reduce lactic acid build-up during strenuous workout sessions.
So, not only does it try to increase your workout intensity, but it could also help you reduce lactic acid build-up during your workout session!
According to the believers of Ostarine MK2866 for muscle building, it gives them a massive advantage over their competition.
They also claim that not only it makes their workout more intense, but they also find it promotes faster muscle recovery time, meaning that they could do more reps before their muscles become sore.
Why is Ostarine popular?
For the people who believe in SARMs, in this case, Ostarine, they mention that they were able to achieve some great benefits by regularly using this substance.
They also mention that with its help in muscle development, they were able to reach their goals at a faster pace.
According to them, this is the best one among many supplements nowadays because it comes loaded with helpful substances that could help increase muscle mass. It could also help improve your stamina in bed and at work.
As you know, most bodybuilders today have been using this to increase the size of their muscles and strength. Aside from that they also claim that it is also good for those who have low protein in their system.
Slowly and steadily, these things are changing. As the number of people who like to eat healthy and clean is increasing day by day.
What are the advantages of Ostarine?
You may find a many benefits of Ostarine by simply typing into Google. It helps to gain lean muscle mass, burn fat etc. But we have found a study from 2009. Yes, only recently everyone started to talk about SARMs but in 2009 there was a experiment done on people suffering certain conditions who gained enormous amount of muscle mass. Read below.
The Warrior Project Ostasize is Ostarine for maximum gains
Abstract of the study
We hope to have an announcement by the end of the summer,” said GTx spokesman McDavid Stilwell. GTx is collaborating with Merck and Co. Inc. to develop Ostarine as part of a broader SARMs clinical development program. SARMs (selective androgen receptor modulators) are a new class of drugs that have the potential to treat musculoskeletal conditions. Results of Phase II clinical trials of Ostarine show that patients suffering from the muscle-wasting condition cancer cachexia gained as much as 1.5 kilograms of body mass.
“This was a promising result,” said CEO Dr. Mitchell Steiner. “Ostarine demonstrated the ability to build lean body mass in a sick cohort of cancer patients, who prior to entry into the study had lost on average more than 8 percent of body weight.” Study results were announced last week at the 2009 annual meeting of the Endocrine Society in Washington. If Ostarine makes it through the U.S. Food and Drug Administration process, it will be the first FDA-approved therapy available for cancer cachexia, said trial investigator Dr. Adrian Dobs, professor of medicine and oncology at Johns Hopkins University School of Medicine.
“There’s really not much out there,” he said. Among a group of 159 patients, the most common side-effects found were fatigue, anemia, nausea and diarrhea. GTx employs 140 people locally and has spent millions since 1997 trying to bring new drugs to market. In the first quarter, the company saw a net loss of $11.3 million; however, losses in the research and development phase are expected for the publicly traded company, leaving investors paying more attention to clinical trials like this. Currently, Toremifene 80 mg, GTx’s drug for prevention of bone fractures in men with prostate cancer, is being reviewed by the FDA. The company has yet to fully develop and bring a drug through the FDA process. GTx earnings primarily come through partnerships with drug companies like Merck and Ipsen. — Lindsay Melvin: 529-2445
This was an amazing achievement done with Ostarine. So have a look on the other benefits that might interest YOU!
1. It Helps You Grow Muscles
Ostarine is the best option you have if you’re looking to gain muscle mass. Apart from its use among athletes and bodybuilders, it is also used to increase muscle mass in cancer patients. Ostarine is quickly absorbed in the body, and so it produces extraordinary results within a short period. This makes it an excellent alternative as you don’t get to deal with all detrimental side effect steroids bring along.
In a study done on the effects of Ostarine on lean muscle mass, it showed that it could increase muscle mass drastically. They used a dosage of 3mg a day and experienced no side effects at all.
MK-2866 is mostly developed to mimic the effects of real steroids but without nasty side effects like gyno, testosterone suppression, and acne.
It has minimal side effects and has been proven to increase muscle mass in basically every study. A recent study showed that both Ligandrol and Ostarine had beneficial effects on muscle structure and metabolism.
MK-2866 is not something to take lightly, it most definitely works to enhance your performance in the gym. WADA also added it to its prohibited list since some athletes used it to enhance their performance.
2. It Increases Your Strength
Ostarine is suitable for you if you’re a bodybuilder or athlete looking to increase your strength. It does not only build muscles, but it also increases muscle strength thereby enhancing your performance in any physical activity.
3. It Builds Your Endurance
Reaching your fitness goals depends on your level of endurance. It doesn’t matter what your goal is; weight loss or bodybuilding, you need endurance. In addition to muscle development and increase in strength, you can be sure of increased endurance whenever you use Ostarine.
4. It Aids Your Healing Process
Injuries during training sessions are everyday thing. It, however, becomes worse when you have a big event that requires full fitness coming up. Luckily, Ostarine speeds up the healing process. You can be sure of a speedy recovery whenever you get injured exercising or during a training session as recent studies have shown that using Ostarine can help you heal up in no time.
5. It is a Treatment for Osteoporosis
Ostarine supplements significantly increase bone strength, and so it is very efficient in the treatment of Osteoporosis, apart from increasing bone strength, it speeds up the bone fracture healing process and enhances your bone formation in the body.
6. It Helps You Build a Healthier Heart
Studies have shown that low muscle mass can result in reduced heart function. Ostraine helps you gain muscle mass, improves muscle quality and also lowers cholesterol levels in the body which leads to a better heart function.
Side effects of Ostarine
As with every supplement taking for a long time and big dosages you may get side effects. With Ostarine there has not been found a proof that provides us with the list of side-effects caused by Ostarine. We only found an article saying that some participants have experienced mild acne and headaches but there has not been mentioned how lond did they take it and how much they took. Therefore, our conclusion is that there might be some side effects when you are running Ostarine for a long time and with big dosages. With the correct use, you should not be worried about side effects.
Citation from the article from the company working with the SARMs for many years:
Although Ostarine shouldn’t cause a full-blown hormonal imbalance, it has been reported to raise blood estradiol to an extent. Based reports we came across so far, the increase is very mild. Unlike steroids, Ostarine shouldn’t cause water retention or trigger dramatic drops in testosterone production. Slight testosterone suppression is still possible and seems to be more likely at higher Ostarine doses.
The side effects users reported include the following:
No increases in muscle size or strength after 5 weeks
Decreased sense of wellness after the first 9 days
Testicle Pain
Joint pain
Reduced strength
Testosterone suppression 4 weeks after stopping it (didn’t do PCT)
Erection difficulties
Disrupted sleep
Low energy
Increased estrogens with high doses
Menstrual cycle imbalances
Acne and skin changes with higher doses
Headaches
Nausea
Baldness
Although uncommon, some users do report gyno flare ups. One side of the nipple can become slightly enlarged and painful. Sometimes both nipples are affected.
Again, it’s unknown if some of the users also took steroids, other drugs, or what the Ostarine content in their product was.
OSTARINE DOSAGE INFORMATION
First of all, MK-2866 has been shown to be effective at very low dosages. I am talking dosages as small as 1mg to 3mg.
However, an average dosage would be between 10 and 30mg a day. There is no scientific evidence that these are better dosages. However, anecdotally these dosages gave more improvements like muscle mass, strength, and recovery.
We definitely wouldn’t advise anyone to go over the clinical dosage, which is 3mg. These dosages have been proven not to give you any adverse effects.
However, higher dosages could possibly mean more side effects.
I personally liked to use ostarine at 10mg for at least 8 weeks while I was cutting down. It immensely helped me with muscle preservation and muscle hardening.
Ostarine is already effective at 1mg a day. However, as you can see, the lean body mass increased drastically when the dosage is increased to 3mg a day.
Therefore many users claim that the ‘sweet spot is between 10 and 30mg per day.
Experienced users do not recommend going above 30mg a day because the higher the dosage, the more side effects you can experience.
When searching for information about a typical cycle, you will see that it’s between 6-12 weeks and ranges from 10-30mg ostarine a day.
We recommend using a Post Cycle Therapy (PCT) to recover from the testosterone suppressive side effects and keep your new muscle gains.
HALF-LIFE
The half-life of Ostarine is about 24 hours. That means if you plan on running a cycle, taking it once a day will be sufficient for having stable levels.
So, it doesn’t matter if you take it in the morning or evening, just in a 24 hours time frame.
Conclusion
Ostarine or MK2866 is probably the most researched SARM out there. It is very beneficial for athletes and bodybuilders. Ostarine is especially good for lean mass and fat burning among other benefits. The side effects are very mild but they do need to be target of further research. As with every supplement, the source is very important. Always make sure, you get what you pay for! Usually, people do not get results not because the product is not working but because they have gotten the cheapest brand and low in quality. Have a look on our offer. We only supply the products that work for our clients.
Disclaimer: The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Nutrition First wants to only put together information from other sources in one place.
[fusion_woo_shortcodes]
2 Comments